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鈻� 鞕检�诫秬韯� 鞚橃儩氇呹车頃欔臣 旯�歆勳嫕 甑愳垬, 甓岇榿鞚� 甑愳垬, 靻§灛鞙� 氚曥偓

霃欔淡雽赌顷欔祼 鞚橃儩氇呹车頃欔臣 旯�歆勳嫕·甓岇榿鞚� 甑愳垬 瓿惦彊鞐瓣惮韺�(鞝�1鞝�鞛� 靻§灛鞙� 氚曥偓(氚曥偓頉勳棸甑�鞗�), 甑愳嫚鞝�鞛� 旯�歆勳嫕 甑愳垬·甓岇榿鞚� 甑愳垬, 瓿惦彊鞝�鞛� Neethu Ramakrishnan 氚曥偓瓿检爼靸�)鞚� 彀�靹鸽寑 歆勲嫧 毵堨护搿� 欤茧�╇皼電� 靹疙彫鞕胳唽韽�觳�(Extracellular vesicle, EV)鞚� 響滊┐ 雼�氚膘�堨潉 響滌��(label) 鞐嗢澊 鞝曤焿 攵勳劃頃� 靾� 鞛堧姅 鞚戈车歆�電� 頇滌毄 鞝勱赴頇旐暀 頂岆灚韽检潉 臧滊皽頄堧嫟.

靹疙彫鞕胳唽韽�觳措姅 靹疙彫臧� 攵勲箘頃橂姅 雮橂吀氙疙劙 韥�旮办潣 鞛呾瀽搿�, 響滊┐ 雼�氚膘�� 臁办劚鞚� 歆堧硲 靸來儨毳� 氚橃榿頃� 鞎�, 鞁犼步韲错枆靹� 歆堩櫂 霌膘潣 鞎§泊靸濌瞼 毵堨护搿� 臧侁磻氚涥碃 鞛堧嫟. 攴鸽煬雮� 靹疙彫鞕胳唽韽�觳搓皜 ‘鞚挫�堨劚’鞚� 臧�歆�瓿� 鞛堨柎 鞁れ牅搿滊姅 韥�旮办檧 雮挫毄氍�, 響滊┐ 雼�氚膘�堨澊 臧侁赴 雼るゴ瓿�, 鞚措ゼ 攵勳劃氩曥澊 鞝曧檿頌� 鞚届柎雮措姅歆� 瓴�歃濏暊 旮办��鞚� 鞐嗢柎 響滌��頇旉皜 鞏措牑鞖� 靸來櫓鞚挫棃雼�. 霕愴暅, 攵勳劃氩� 雽�攵�攵勳澊 順曣磻 響滌�� 霌� 氤勲弰鞚� 霛茧波毵� 瓿检爼鞚� 鞖旉惮頃橁碃 鞛堨柎 響滌��頇� 頃滉硠搿� 歆�鞝侂悙雼�.

甓岇榿鞚� 甑愳垬韺�鞚� 靹疙彫 鞙犽灅 瓿奠爼鞙茧�� 韥�旮半姅 霃欖澕頃橁碃 響滊┐ 雼�氚膘�� 順曧儨毳� 雼�瓿勳爜鞙茧�� 雼るゴ瓴� 臁办爤頃� 雮橂吀氩犾��韥�(nanovesicle)鞚� 鞝滌瀾頄堧嫟. 鞝滌瀾 瓿检爼鞐愳劀 鞎岇笭頃橃澊毹鸽硲鞚� 氚旍澊鞓る�堨护搿� 鞎岆牑歆� 氩犿儉 鞎勲皜搿滌澊霌滊ゼ 頇滌毄頃橁碃, 氩犿儉 鞎勲皜搿滌澊霌滉皜 雵岇�堩櫂鞐愳劀 雮橅儉雮措姅 鞚戩�� 韸轨劚鞚� 頇滌毄頃� 響滊┐ 雼�氚膘�堨潣 臁办劚鞚� 鞐办啀鞝侅溂搿� 氤�頇旍嫓韨る┐靹� 韥�旮�·雮挫毄氍� 氤�靾橂ゼ 韱奠牅頄堧嫟.

旯�歆勳嫕 甑愳垬韺�鞚� 氙胳劯 鞝勱饭(Interdigitated microelectrode)鞚� 毵岆摐電� 鞝勱赴鞛レ溂搿� 雮橂吀氩犾��韥� 毵� 響滊┐鞚� 韮愳龚頃橂姅 鞛勴敿雿橃姢 攵勱磻 靹检劀毳� 甑�於曧晿瓿�, 毹胳嫚霟�雼濎溂搿� 鞛勴敿雿橃姢 攵勱磻 鞀ろ帣韸鸽熂鞚� 攵勲�橅晿電� 攵勳劃 韺岇澊頂勲澕鞚胳潉 臧滊皽頄堧嫟. 攴� 瓴瓣臣 順曣磻 響滌�� 鞐嗢澊 鞝勱赴 鞁犿樃毵岇溂搿� 響滊┐ 雼�氚膘�� 順曧儨 彀�鞚� 攵勴暣鞐� 靹标车頄堧嫟.

鞐瓣惮韺�鞐� 霐半ゴ氅�, 鞚措矆 瓴瓣臣電� 氍胳牅毳� 霋れ�戩柎 攵勳劃氩曥潉 瓴�歃濏暊 靾� 鞛堧姅 ‘響滌�� 鞁滊��’毳� 歆侅爲 靹り硠頃� 瓴冹溂搿�, 靹疙彫鞕胳唽韽�觳� 響滊┐ 雼�氚膘�� 攵勳劃鞐� ‘旮办�� 鞁滊��’鞕� ‘韺愲弲旮�’毳� 霃欖嫓鞐� 鞝滉车頃� 瓴冹溂搿� 韽夑皜氚涥碃 鞛堧嫟. 雮橂吀氩犾��韥挫潃 頄ロ泟 臧滊皽霅橂姅 EV 歆勲嫧 靹检劀霌れ潣 靹彪姤鞚� 牍勱祼·瓴�歃濏晿電� 旮办��氍检�堧��, 鞛勴敿雿橃姢·毹胳嫚霟�雼� 頂岆灚韽检潃 霛茧波 鞐嗠姅 鞁犾啀 攵勳劃 霃勱惮搿� 臧侁皝 頇滌毄霅� 靾� 鞛堧嫟.

靻§灛鞙� 氚曥偓電� “鞚挫�堨劚鞚� 韱奠牅頃� 響滌�� 氩犾��韥� 雿曤秳鞐� 靹检劀 鞁犿樃鞐愳劀 響滊┐ 雼�氚膘�堨潣 旮办棳毵岇潉 攵勲Μ頃� 頃欖姷鞁滍偓 靾� 鞛堨棃雼�”氅�, “靹疙彫鞕胳唽韽�觳� 攵勳劃鞚� 響滌��頇旊ゼ 頄ロ暅 於滊皽鞝愳澊 霅橁父 旮半寑頃滊嫟”瓿� 毵愴枅雼�. 旯�歆勳嫕 甑愳垬電� “氚旍澊鞓れ劶靹滌檧 鞚戈车歆�電�, 攴鸽Μ瓿� 雼�氚膘�堦车頃� 旮办垹鞚� 瓴绊暕頄堨潉 霑� 旮办�� 攵勳劃鞚� 頃滉硠毳� 鞏措柣瓴� 攴闺车頃� 靾� 鞛堧姅歆� 氤挫棳欷� 靷�搿�”霛缄碃 氚濏様瓿�, 甓岇榿鞚� 甑愳垬電� “靹疙彫 旮半皹 雮橂吀氩犾��韥� 瓿淀暀鞚� 歆勲嫧·攵勳劃 旮办垹 瓴�歃濎潣 旮办�� 頂岆灚韽检溂搿� 頇曥灔霅� 靾� 鞛堨潓鞚� 頇曥澑頄堧嫟”瓿� 鞝勴枅雼�.

頃滍幐, 鞚措矆 鞐瓣惮電� 瓿柬暀旮办垹鞝曤炒韱奠嫚攵� 鞛�鞗愳潣 頃滉淡鞐瓣惮鞛�雼�(NRF, 2023R1A2C2007147, RS-2024-00416117)瓿� 瓿柬暀旮办垹靷�鞐呿檾歆勴潵鞗�(COMPA, RS-2025-17632971)鞚� 歆�鞗愳潉 氚涭晞 靾橅枆霅愲嫟. 鞐瓣惮 靹标臣電� ‘Machine-Learning-Assisted Impedance Component Analysis Enables Standardizable Surface Protein Analysis of Extracellular Vesicles Using Engineered Nanovesicles’霛茧姅 鞝滊�╈溂搿� 甑�鞝� 頃欖垹歆� Advanced Science(IF 14.1)鞐� 氚滍憸霅愲嫟.